8 Games Like Plague Inc

Games Like Plague Inc This deadly collection of games like Plague Inc. features other games with an emphasis on simulating the spread of disease across the globe.

Plague Inc. is a mobile title (Windows Phone, iOS and Android) that sees players creating their own devastating plague to take over and infect the entire population. Giving players control over the elements of their ever evolving pathogen and combining it with simulation on a global scale Plague Inc. creates a unique gameplay mix.

Starting with your patient zero the direction that your pathogen takes is in the hands of the player as they select from a range of transmissions, symptoms and abilities to enhance infection, counter attempts to create a cure and become deadly to those infected. Balancing these strategy elements with your current infected locations and plague type is the key to taking over every corner of the globe.

The games like Plague Inc. below are similar strategy titles that have an emphasis on disease creation or control and the downfall of the human race. In these titles you’ll carefully choose infection or cure options as you seek to save or end the world or play a role in other world ending scenarios. Platforms include mobile (iOS and Android) along with PC and browser variants and thus is also appropriate for those seeking games like Plague Inc: Evolved, the popular game sequel.


Infectonator (or Infectonator 2 based on web versions) is a game that sees you taking control of zombie hordes with the objective of taking over the world one location at a time. Available for free on iOS, Android and browser with a freemium model for additional content. After infecting your way through the tutorial basics players are greeted with the world map, which is just waiting to be taken over by the zombies under your command. Each country is further split by town which each come with th...[Read Review]

8 User Avg (4 votes)


DEFCON is a RTS title that looks into a potentially dark future with the world at large scale nuclear war. Drawing heavily from the Cold War era the game is just as much about psychological warfare than the missiles that fly around the globe. Playing as a General in the safety of your underground bunker you’ll command your countries defences and silos as you try to wipe your enemies from the planet. This requires players to attack the population of opposing nations while defending their ow...[Read Review]

8 User Avg (5 votes)

First Strike

First Strike takes strategy to the nuclear level with a mobile title that has you researching deadly weapons and launching them against countries. Available for iOS and Android (free) First Strike joins the ranks of titles such as Plague Inc where victory is a world ending scenario. Despite the dark setting those that can look beyond that will find an interesting mobile strategy title that is great in short mobile bursts while still providing some longevity to your purchase. A later release with...[Read Review]

7.8 User Avg (4 votes)

Infect Them All 2 : Zombies

Infect Them All 2 : Zombies is a campaign orientated game that sees you attempting to infect all the humans on each map. Available on iOS only the base game is available for free with a paid version with additional zombie champions for you to control. Building heavily on the original and borrowing much from the game assets Infect Them All 2: Zombies is more about refinement of gameplay than re-invention which might turn some fans of the original off since it looks and plays like essentially the ...[Read Review]

7.5 User Avg (4 votes)

Pandemic: The Board Game

Turning the tables on the typical disease outbreak game, Pandemic: The Board Game brings the actual board game to mobile and sees you playing the role of disease fighting team. Just like the board game you’ll be keeping a total of 4 diseases at bay across the world while also seeking out cures. Playing as 4 different specialists (controlled by a single player or multiple players) its a race against the clock as outbreaks spread from city to city. As this mobile game stems from a board game...[Read Review]

6.8 User Avg (5 votes)

Bio Inc.

Taking the mobile strategy genre down to the human body level is Bio Inc. a unique title that is all about designing the perfect disease to destroy one element of the body at a time. Despite this quite morbid synopsis the strategy is there and combines with a well-designed UI to make for a challenging unique experience. As you would expect to see in a mobile title everything is guided by the tap of a finger as you browse through game menus, collect bio points and monitor the vital signs of your ...[Read Review]

6.5 User Avg (4 votes)

Infection Bio War

Taking the popular formula and style of Pandemic 2, Infection Bio War has you taking over the planet with your own unique disease one country at a time. Available for free to play on your iOS and Android devices you’ll be able to cause havoc wherever you are. Each game in Infection Bio War has you naming your new disease and choosing a starting country location. For those familiar with similar disease spreading games you’ll instantly appreciate the ability to start in one of the more...[Read Review]

6.2 User Avg (4 votes)

Pandemic 2

Starting in 2008 Pandemic 2 explores the very real possibility of a disease outbreak crippling the world economy. Human confidence is at an all time high in the world of Pandemic 2 after surviving the disease of the original. With shipyards, airports and hospitals all open for business its your job to bring the hospitals to stand still and ride transport across the globe. Playing as your own disease and starting in a random corner of said globe you’re objective is to infect every single co...[Read Review]

5.8 User Avg (4 votes)
Games Like Plague Inc